Maurizio Seracini is the director of the Center for Interdisciplinary Science for Art, Architecture, and Archaeology (CISA3) at the University of California San Diego's California Institute for Telecommunications and Information Technology (Calit2). He is a pioneer in the use of multispectral imaging and other diagnostic tools as well as analytical technologies as applied to works of art and structures. He has studied more than 2,500 works of art and historic buildings.

Seracini joined Calit2 in 2006, more than thirty years after graduating from UCSD with a B.A. in bioengineering in 1973. Seracini returned to Italy for graduate school and received the Laurea degree in electronic engineering from the University of Padua, where he went on to study medicine. From 1975-77, he participated in the Leonardo Project to locate the long-lost fresco, "The Battle of Anghiari" (a project sponsored by the Armand Hammer Foundation, Kress Foundation, and the Smithsonian Institution). In 1977, Seracini established Editech, a Florence-based company that was the first to provide art and architectural diagnostic services. In 1979 he co-founded the Interdisciplinary Center for Ultrasonic Diagnostics in Medicine, also in Florence.

Since 1980, Seracini has lectured at institutions in Italy and abroad, including Argentina and the United States. He has been an adjunct professor at the University of Florence in its School of Engineering, School of Architecture, and School of Natural, Physical, and Mathematical Sciences. He has also lectured at the International University of Art in Florence; the University of Ca' Foscari (Venice); and the University of Calabria (Cosenza), where he remains an adjunct research professor in the School of Engineering and the School of Arts and Humanities.