America’s agricultural landscape is now 48 times more toxic to honeybees, and likely other insects, than it was 25 years ago, almost entirely due to widespread use of so-called neonicotinoid pesticides, according to a new study published today in the journal PLOS One.

This enormous rise in toxicity matches the sharp declines in bees, butterflies, and other pollinators as well as birds, says co-author Kendra Klein, senior staff scientist at Friends of the Earth US.

“This is the second Silent Spring. Neonics are like a new DDT, except they are a thousand times more toxic to bees than DDT was,” Klein says in an interview.

Using a new tool that measures toxicity to honey bees, the length of time a