At the University of Florida, Parkinson’s disease patient Russell Price undergoes surgery to implant a deep brain stimulation (DBS) lead that will deliver electrical impulses to motion-controlling parts of his brain, treatment which has been shown to provide substantial relief from symptoms in appropriately selected patients. Additional improvement in some patients may also derive from the mere expectation that the procedure will help—the so-called placebo effect. “It’s not a magical thing,” says neurologist Michael Okun. “It’s another part of the brain that is producing a beneficial effect not directly related to the action of our treatment.” Photographed and filmed at McKnight Brain Institute, University of Florida

The pilgrim wasn’t sure he’d make it to the Chapel of Grace. It was agony to walk at all, let alone endure the 70 miles that thousands of believers trek each year to behold an enshrined wood statue: the Black Madonna of Altötting.

Richard Mödl had recently broken his heel, but in 2003 he was determined to complete his first pilgrimage from Regensburg to Altötting, Germany. He figured if the pain got too bad he could always hitch a ride. But he had a deep faith in the Virgin Mary’s ability to deliver him. So he walked. And walked. “When you are on your way to Altötting, you almost don’t feel the pain,” he says.

Today, at 74, Mödl has a warm smile and a wiry frame that looks as if it could survive a charging rhinoceros. Since the healing of his foot, he’s made the pilgrimage 12 more times, and he’s a passionate believer in its transformative power.

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