See-Through Mouse Brains Created; May Aid Medical Scans

Transparent organs, embryos have real "wow factor," expert says.

Known as Scale, the new chemical makes body tissue so crystal clear that light can penetrate deeply enough for researchers to directly see fluorescent markers embedded in cells and other structures.

This advance could unveil new frontiers in medical imaging, according to its creators. (See pictures: "Glowing Animals—Beasts Shining for Science.")

"Our current experiments are focused on the mouse brain, but applications are neither limited to mice nor to the brain," Atsushi Miyawaki, of Japan's RIKEN Brain Science Institute, said in a press statement.

We envision using Scale on other organs such as the heart, muscles, and kidneys and on tissues from primate and human biopsy samples."

(Related picture: "See-Through Frog Bred in Japan.")

"I've worked in brain imaging for 20

DON'T MISS THE REST OF THIS STORY!
Create a free account to continue and get unlimited access to hundreds of Nat Geo articles, plus newsletters.

Create your free account to continue reading

No credit card required. Unlimited access to free content.
Or get a Premium Subscription to access the best of Nat Geo - just $19
SUBSCRIBE

Read This Next

AI can help you plan your next trip—if you know how to ask.
Did this mysterious human relative bury its dead?
This new birth control for cats doesn't require surgery

Go Further

Subscriber Exclusive Content

Why are people so dang obsessed with Mars?

How viruses shape our world

The era of greyhound racing in the U.S. is coming to an end

See how people have imagined life on Mars through history

See how NASA’s new Mars rover will explore the red planet

Why are people so dang obsessed with Mars?

How viruses shape our world

The era of greyhound racing in the U.S. is coming to an end

See how people have imagined life on Mars through history

See how NASA’s new Mars rover will explore the red planet

Why are people so dang obsessed with Mars?

How viruses shape our world

The era of greyhound racing in the U.S. is coming to an end

See how people have imagined life on Mars through history

See how NASA’s new Mars rover will explore the red planet