See-Through Mouse Brains Created; May Aid Medical Scans
Transparent organs, embryos have real "wow factor," expert says.
Known as Scale, the new chemical makes body tissue so crystal clear that light can penetrate deeply enough for researchers to directly see fluorescent markers embedded in cells and other structures.
This advance could unveil new frontiers in medical imaging, according to its creators. (See pictures: "Glowing Animals—Beasts Shining for Science.")
"Our current experiments are focused on the mouse brain, but applications are neither limited to mice nor to the brain," Atsushi Miyawaki, of Japan's RIKEN Brain Science Institute, said in a press statement.
We envision using Scale on other organs such as the heart, muscles, and kidneys and on tissues from primate and human biopsy samples."
(Related picture: "See-Through Frog Bred in Japan.")
"I've worked in brain imaging for 20