The Blind Locksmith Continued: An Update from Joe Thornton

I’ve written a few times here about the ongoing work of Joe Thornton, a biologist at the University of Oregon and the Howard Hughes Medical Institute. Thornton studies how molecules evolve over hundreds of millions of years. He does so by figuring out what the molecules were like in the distant past and recreating those ancestral forms in his lab to see how they worked. I first wrote about his work looking at how one molecule in our cells evolved from one function to another (here, here, and here). [Update: These links are now fixed.]

Most recently, I wrote in the New York Times about his latest experiment, in which he and his colleagues found that

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