Picture of a group of French models in line to be vaccinated against smallpox.

Why smallpox vaccines fell out of use—and what that means for monkeypox

Smallpox vaccines have been approved for monkeypox. But experts warn that many questions remain about the protection they provide and how to best administer them.

Members of the Association of French Models line up for their smallpox vaccinations, October 2, 1955. A mass vaccination campaign led to the eradication of smallpox in 1980. Although the vaccine is no longer routine, it's in demand once again during the monkeypox outbreak.
Photograph by FPG, Hulton Archive/Getty Images
This content is Subscriber-Exclusive
You must have a National Geographic subscription to explore this article.

Read This Next

Is banning fishing bad for fishermen? Not in this marine reserve
SeaWorld allegedly violated the Animal Welfare Act. Why is it still open?
'World’s worst shipwreck' was bloodier than we thought

Go Further

Subscriber Exclusive Content

Why are people so dang obsessed with Mars?

How viruses shape our world

The era of greyhound racing in the U.S. is coming to an end

See how people have imagined life on Mars through history

See how NASA’s new Mars rover will explore the red planet

Why are people so dang obsessed with Mars?

How viruses shape our world

The era of greyhound racing in the U.S. is coming to an end

See how people have imagined life on Mars through history

See how NASA’s new Mars rover will explore the red planet

Why are people so dang obsessed with Mars?

How viruses shape our world

The era of greyhound racing in the U.S. is coming to an end

See how people have imagined life on Mars through history

See how NASA’s new Mars rover will explore the red planet