Residents of Mashiki in Kumamoto Prefecture walk past homes was damaged by the temblor on Thursday.
See the Devastation Caused by the Recent Earthquakes in Japan
The quakes are the largest to strike the region since the 2011 disaster.
A magnitude 7 earthquake rocked Japan's Kyushu Island early Saturday morning local time, just two days after a magnitude 6.2 temblor struck the region. The full extent of the damage is currently unknown, but it is expected to be substantial, and a tsunami warning has been issued.
The latest quake struck 8 miles (13 kilometers) south-southeast of Ueki, the epicenter of the April 14 tremor that left 9 dead and 800 injured, reports the U.S. Geological Survey.
Experts say more quakes are possible, though it's most likely they would be smaller than magnitude 7. The latest earthquake was the strongest to hit Japan since the devastating 2011 event that triggered the Fukushima nuclear disaster.