astronaut Scott Kelly along with his brother, former Astronaut Mark Kelly.

One-of-a-kind study of astronaut twins hints at spaceflight’s health effects

By comparing Scott Kelly to his twin brother on Earth, scientists are starting to untangle the genetic, physical, and cognitive toll of being in space.

Astronaut Scott Kelly (right) and his twin brother, former astronaut Mark Kelly, attend a media event ahead of Scott's one-year mission aboard the International Space Station.
Photograph by Robert Markowitz, NASA

Medical science loves twins—the near-perfect physical and genetic match makes for ideal conditions to compare and contrast human responses to environmental change. And when the twins also happen to be astronauts, it’s like striking research gold. That’s why NASA leapt at the opportunity when U.S. astronaut Scott Kelly suggested that he and his identical twin brother, Mark, could be test subjects for an investigation on the health effects of long-term space flight.

A first-of-its-kind study was hatched: Scott would travel to the International Space Station and stay there for one year, working and living the life of an astronaut in the confines of microgravity. Meanwhile, back on Earth, Mark would serve as a genetically identical ground control, working and living the

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