Scientists and mathematicians who are making strides in human health, developing new technologies, and expanding our knowledge of the cosmos are among the recipients of the 2019 Breakthrough Prizes. Each major prize, awarded in the categories of life sciences, fundamental physics, and mathematics, comes with a $3-million check.

Sponsored by Silicon Valley notables such as Yuri Milner and Mark Zuckerberg, it’s one of the largest science prizes offered, and this year’s awards ceremony, to be broadcast live November 4 on National Geographic, promises to be an appropriately star-studded affair. With Pierce Brosnan hosting, the Breakthrough Prize winners will accept their awards from a variety of presenters, including actors such as Lupita Nyong’o and Zoe Saldana.

“I’m extremely grateful to have